{"id":4552,"date":"2026-03-20T21:00:55","date_gmt":"2026-03-21T03:00:55","guid":{"rendered":"https:\/\/victorvizcaino.com\/blog\/?p=4552"},"modified":"2026-03-20T21:00:55","modified_gmt":"2026-03-21T03:00:55","slug":"cofepris-sanitary-notices-mexico","status":"publish","type":"post","link":"https:\/\/victorvizcaino.com\/blog\/cofepris-sanitary-notices-mexico\/","title":{"rendered":"\ud83c\udfe5 COFEPRIS Sanitary Notices: Complete Guide for Food and Health Businesses"},"content":{"rendered":"<p class=\"ds-markdown-paragraph\">If your business is related to food, beverages, supplements, cosmetics, health services, or medical products, you need to comply with\u00a0<strong>COFEPRIS sanitary notices<\/strong>. This is the health authority in Mexico that regulates everything that impacts people&#8217;s health.<\/p>\n<p class=\"ds-markdown-paragraph\">In this article, I explain what COFEPRIS is, what procedures exist, who needs them, and how to comply with regulations to operate without legal risks.<\/p>\n<hr \/>\n<h2>\ud83d\udccc What is COFEPRIS?<\/h2>\n<p class=\"ds-markdown-paragraph\"><strong>COFEPRIS<\/strong>\u00a0(Federal Commission for Protection against Health Risks) is the agency responsible for regulating and controlling products, services, and establishments that can affect public health.<\/p>\n<p class=\"ds-markdown-paragraph\">Its main function is to protect consumers by ensuring products and services comply with established health standards.<\/p>\n<blockquote>\n<p class=\"ds-markdown-paragraph\">\u26a0\ufe0f\u00a0<strong>Important:<\/strong>\u00a0Operating without the corresponding sanitary notices can result in fines, closures, or even product seizure.<\/p>\n<\/blockquote>\n<hr \/>\n<h2>\ud83e\uddfe What Are Sanitary Notices?<\/h2>\n<p class=\"ds-markdown-paragraph\"><strong>Sanitary notices<\/strong>\u00a0are the procedures through which you inform COFEPRIS that you will operate an establishment, manufacture a product, or carry out a regulated activity. There are two main categories:<\/p>\n<h3>1. Operation Notice<\/h3>\n<p class=\"ds-markdown-paragraph\">Filed before starting operations of an establishment. Applies to:<\/p>\n<ul>\n<li class=\"ds-markdown-paragraph\">Restaurants, cafeterias, dining halls<\/li>\n<li class=\"ds-markdown-paragraph\">Beauty salons, barbershops, spas<\/li>\n<li class=\"ds-markdown-paragraph\">Clinics, medical offices, laboratories<\/li>\n<li class=\"ds-markdown-paragraph\">Pharmacies, health food stores<\/li>\n<li class=\"ds-markdown-paragraph\">Gyms, sports centers<\/li>\n<\/ul>\n<blockquote>\n<p class=\"ds-markdown-paragraph\">\ud83d\udca1\u00a0<strong>It is not prior authorization<\/strong>, it is a notification. But if you don&#8217;t file it, you cannot operate legally.<\/p>\n<\/blockquote>\n<h3>2. Health Responsible Party Notice<\/h3>\n<p class=\"ds-markdown-paragraph\">Designates the person in charge of ensuring the establishment complies with health standards. It is mandatory for:<\/p>\n<ul>\n<li class=\"ds-markdown-paragraph\">Food and beverage establishments<\/li>\n<li class=\"ds-markdown-paragraph\">Health establishments<\/li>\n<li class=\"ds-markdown-paragraph\">Pharmacies and laboratories<\/li>\n<\/ul>\n<blockquote>\n<p class=\"ds-markdown-paragraph\">\u26a0\ufe0f\u00a0<strong>The health responsible party must have a professional license<\/strong>\u00a0in areas such as nutrition, chemistry, biology, pharmacy, or medicine.<\/p>\n<\/blockquote>\n<hr \/>\n<h2>\ud83d\udc64 Who Needs COFEPRIS Procedures?<\/h2>\n<p class=\"ds-markdown-paragraph\">All businesses that fall under these categories must comply with health regulations:<\/p>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within _1210dd7 c03cafe9\">\n<table>\n<thead>\n<tr>\n<th>Category<\/th>\n<th>Examples<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Food and beverages<\/strong><\/td>\n<td>Restaurants, cafeterias, diners, industrial kitchens, food processors, craft breweries<\/td>\n<\/tr>\n<tr>\n<td><strong>Supplements and nutraceuticals<\/strong><\/td>\n<td>Manufacturers, distributors, importers<\/td>\n<\/tr>\n<tr>\n<td><strong>Cosmetics and personal care<\/strong><\/td>\n<td>Manufacturers, importers, beauty salons<\/td>\n<\/tr>\n<tr>\n<td><strong>Medical products<\/strong><\/td>\n<td>Manufacturers, distributors, pharmacies<\/td>\n<\/tr>\n<tr>\n<td><strong>Health services<\/strong><\/td>\n<td>Clinics, medical offices, laboratories, hospitals, medical spas<\/td>\n<\/tr>\n<tr>\n<td><strong>Chemical substances<\/strong><\/td>\n<td>Manufacturers, distributors<\/td>\n<\/tr>\n<tr>\n<td><strong>Tobacco and alcoholic beverages<\/strong><\/td>\n<td>Commercial distributors, importers<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<blockquote>\n<p class=\"ds-markdown-paragraph\">\ud83d\udca1\u00a0<strong>If your business touches health or human consumption, you likely need a sanitary notice.<\/strong><\/p>\n<\/blockquote>\n<hr \/>\n<h2>\ud83d\udccb Types of COFEPRIS Procedures<\/h2>\n<h3>For establishments:<\/h3>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within _1210dd7 c03cafe9\">\n<table>\n<thead>\n<tr>\n<th>Procedure<\/th>\n<th>Description<\/th>\n<th>Deadline<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Operation notice<\/strong><\/td>\n<td>Notification to operate an establishment<\/td>\n<td>Before opening<\/td>\n<\/tr>\n<tr>\n<td><strong>Health responsible party notice<\/strong><\/td>\n<td>Designation of health supervisor<\/td>\n<td>Before opening<\/td>\n<\/tr>\n<tr>\n<td><strong>Sanitary license<\/strong><\/td>\n<td>Permit to manufacture products<\/td>\n<td>Prior to manufacturing<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h3>For products:<\/h3>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within _1210dd7 c03cafe9\">\n<table>\n<thead>\n<tr>\n<th>Procedure<\/th>\n<th>Description<\/th>\n<th>Validity<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Sanitary registration<\/strong><\/td>\n<td>Authorization to commercialize a product<\/td>\n<td>5 years (renewable)<\/td>\n<\/tr>\n<tr>\n<td><strong>Sanitary notification<\/strong><\/td>\n<td>For low-risk products (some cosmetics, supplements)<\/td>\n<td>5 years<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<blockquote>\n<p class=\"ds-markdown-paragraph\">\u26a0\ufe0f\u00a0<strong>Sanitary registrations are mandatory for medications, miracle products, supplements with specific properties, and medical devices.<\/strong><\/p>\n<\/blockquote>\n<hr \/>\n<h2>\ud83d\udccb General Requirements for Operation Notice<\/h2>\n<p class=\"ds-markdown-paragraph\">Requirements may vary by business type, but generally include:<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>Basic documentation:<\/strong><\/p>\n<ul>\n<li class=\"ds-markdown-paragraph\">Notice application form (COFEPRIS format)<\/li>\n<li class=\"ds-markdown-paragraph\">Official ID of owner or legal representative<\/li>\n<li class=\"ds-markdown-paragraph\">Proof of address of the establishment<\/li>\n<li class=\"ds-markdown-paragraph\">Municipal operating license<\/li>\n<li class=\"ds-markdown-paragraph\">Land use permit<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\"><strong>Technical documentation (depending on business type):<\/strong><\/p>\n<ul>\n<li class=\"ds-markdown-paragraph\">Architectural plan of the establishment<\/li>\n<li class=\"ds-markdown-paragraph\">List of equipment and utensils<\/li>\n<li class=\"ds-markdown-paragraph\">Cleaning and disinfection program<\/li>\n<li class=\"ds-markdown-paragraph\">Temperature control (for food businesses)<\/li>\n<li class=\"ds-markdown-paragraph\">Supplier records<\/li>\n<li class=\"ds-markdown-paragraph\">Food handling training certificate (for food businesses)<\/li>\n<\/ul>\n<blockquote>\n<p class=\"ds-markdown-paragraph\">\ud83d\udca1\u00a0<strong>You can check specific requirements on the\u00a0<a href=\"https:\/\/www.gob.mx\/cofepris\" target=\"_blank\" rel=\"noopener noreferrer\">COFEPRIS<\/a>\u00a0portal.<\/strong><\/p>\n<\/blockquote>\n<hr \/>\n<h2>\ud83e\udded How to Complete the Procedure?<\/h2>\n<h3>Step by step:<\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>1. Identify the procedure you need<\/strong><br \/>\nBased on your business type, determine whether you need an operation notice, sanitary registration, or both.<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>2. Prepare your documentation<\/strong><br \/>\nGather all requirements according to your business type. Ensure they are complete.<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>3. Enter the COFEPRIS portal<\/strong><br \/>\nThe procedure is completed online through the COFEPRIS Single Window.<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>4. Complete the form and attach documents<\/strong><br \/>\nFollow the system instructions and upload the required files.<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>5. Make the payment<\/strong><br \/>\nGenerate the payment slip and pay the corresponding fees.<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>6. Receive your acknowledgment<\/strong><br \/>\nOnce submitted, you receive an acknowledgment proving you filed the notice.<\/p>\n<blockquote>\n<p class=\"ds-markdown-paragraph\">\u26a0\ufe0f\u00a0<strong>The operation notice does not require prior approval<\/strong>, but it must be filed before operating.<\/p>\n<\/blockquote>\n<hr \/>\n<h2>\u23f3 Timelines and Approximate Costs<\/h2>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within _1210dd7 c03cafe9\">\n<table>\n<thead>\n<tr>\n<th>Procedure<\/th>\n<th>Timeline<\/th>\n<th>Approximate Cost<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Operation notice<\/strong><\/td>\n<td>Immediate (acknowledgment)<\/td>\n<td>$1,000 &#8211; $3,000 MXN<\/td>\n<\/tr>\n<tr>\n<td><strong>Health responsible party notice<\/strong><\/td>\n<td>Immediate (acknowledgment)<\/td>\n<td>$500 &#8211; $1,500 MXN<\/td>\n<\/tr>\n<tr>\n<td><strong>Sanitary registration<\/strong><\/td>\n<td>30 &#8211; 90 business days<\/td>\n<td>$5,000 &#8211; $15,000 MXN<\/td>\n<\/tr>\n<tr>\n<td><strong>Sanitary notification<\/strong><\/td>\n<td>Immediate to 15 days<\/td>\n<td>$2,000 &#8211; $5,000 MXN<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<blockquote>\n<p class=\"ds-markdown-paragraph\">\ud83d\udca1\u00a0<strong>Costs vary by product type, establishment size, and procedure duration.<\/strong><\/p>\n<\/blockquote>\n<hr \/>\n<h2>\ud83d\udd0d COFEPRIS Inspections<\/h2>\n<p class=\"ds-markdown-paragraph\">COFEPRIS conducts verification visits to ensure establishments comply with regulations.<\/p>\n<h3>What do they inspect?<\/h3>\n<ul>\n<li class=\"ds-markdown-paragraph\">Sanitary conditions of the establishment<\/li>\n<li class=\"ds-markdown-paragraph\">Food or product handling<\/li>\n<li class=\"ds-markdown-paragraph\">Documentation and notices<\/li>\n<li class=\"ds-markdown-paragraph\">Designated health responsible party<\/li>\n<li class=\"ds-markdown-paragraph\">Control records<\/li>\n<\/ul>\n<h3>What happens if you don&#8217;t comply?<\/h3>\n<ul>\n<li class=\"ds-markdown-paragraph\">Financial fines<\/li>\n<li class=\"ds-markdown-paragraph\">Temporary closure<\/li>\n<li class=\"ds-markdown-paragraph\">Permanent closure<\/li>\n<li class=\"ds-markdown-paragraph\">Product seizure<\/li>\n<\/ul>\n<blockquote>\n<p class=\"ds-markdown-paragraph\">\u26a0\ufe0f\u00a0<strong>Fines can range from a few thousand to hundreds of thousands of pesos, depending on the severity of the violation.<\/strong><\/p>\n<\/blockquote>\n<hr \/>\n<h2>\ud83e\uddea Food Business: Specific Requirements<\/h2>\n<p class=\"ds-markdown-paragraph\">If your business involves food and beverages, in addition to the operation notice, you need:<\/p>\n<ul>\n<li class=\"ds-markdown-paragraph\"><strong>Food handling:<\/strong>\u00a0Mandatory training for food handlers<\/li>\n<li class=\"ds-markdown-paragraph\"><strong>Temperature control:<\/strong>\u00a0Refrigerators and measuring equipment<\/li>\n<li class=\"ds-markdown-paragraph\"><strong>Cleaning and disinfection program:<\/strong>\u00a0Documented protocol<\/li>\n<li class=\"ds-markdown-paragraph\"><strong>Pest control:<\/strong>\u00a0Fumigation records<\/li>\n<li class=\"ds-markdown-paragraph\"><strong>Water supply:<\/strong>\u00a0Water quality certificate<\/li>\n<\/ul>\n<blockquote>\n<p class=\"ds-markdown-paragraph\">\ud83d\udca1\u00a0<strong>Restaurants and industrial kitchens require prior inspection in some municipalities.<\/strong><\/p>\n<\/blockquote>\n<hr \/>\n<h2>\ud83e\uddea Health Business: Specific Requirements<\/h2>\n<p class=\"ds-markdown-paragraph\">If your business involves health services (clinics, medical offices, laboratories):<\/p>\n<ul>\n<li class=\"ds-markdown-paragraph\"><strong>Health responsible party with professional license<\/strong><\/li>\n<li class=\"ds-markdown-paragraph\"><strong>Sanitary license for the establishment<\/strong><\/li>\n<li class=\"ds-markdown-paragraph\"><strong>Medical equipment registration<\/strong><\/li>\n<li class=\"ds-markdown-paragraph\"><strong>Hazardous biological-infectious waste management program<\/strong><\/li>\n<li class=\"ds-markdown-paragraph\"><strong>Sterilization control<\/strong><\/li>\n<\/ul>\n<blockquote>\n<p class=\"ds-markdown-paragraph\">\u26a0\ufe0f\u00a0<strong>Health establishments have stricter requirements due to health risk.<\/strong><\/p>\n<\/blockquote>\n<hr \/>\n<h2>\ud83d\udd04 Relationship with Other Procedures<\/h2>\n<p class=\"ds-markdown-paragraph\">COFEPRIS sanitary notices are connected to:<\/p>\n<ul>\n<li class=\"ds-markdown-paragraph\"><strong>Municipal operating license:<\/strong>\u00a0Required for the sanitary notice<\/li>\n<li class=\"ds-markdown-paragraph\"><strong>Land use permit:<\/strong>\u00a0Base requirement<\/li>\n<li class=\"ds-markdown-paragraph\"><strong>Civil Protection approval:<\/strong>\u00a0Required for inspection<\/li>\n<li class=\"ds-markdown-paragraph\"><strong>Trademark registration with IMPI:<\/strong>\u00a0For commercialized products<\/li>\n<\/ul>\n<blockquote>\n<p class=\"ds-markdown-paragraph\">\ud83d\udca1\u00a0<strong>Without the sanitary notice, you cannot legally operate in regulated businesses.<\/strong><\/p>\n<\/blockquote>\n<hr \/>\n<h2>\ud83d\udcda Useful Internal Links<\/h2>\n<ul>\n<li class=\"ds-markdown-paragraph\"><a href=\"https:\/\/victorvizcaino.com\/blog\/operating-license-mexico\/\">Operating License in Mexico<\/a><\/li>\n<li class=\"ds-markdown-paragraph\"><a href=\"https:\/\/victorvizcaino.com\/blog\/land-use-permit-mexico\/\">Land Use Permit: Complete Guide<\/a><\/li>\n<li class=\"ds-markdown-paragraph\"><a href=\"https:\/\/victorvizcaino.com\/blog\/civil-protection-approval-mexico\/\">Civil Protection Approval<\/a><\/li>\n<li class=\"ds-markdown-paragraph\"><a href=\"https:\/\/victorvizcaino.com\/blog\/legal-procedures-open-business-mexico\/\">Legal Procedures to Register Your Business<\/a><\/li>\n<\/ul>\n<hr \/>\n<h2>\u2705 Conclusion<\/h2>\n<p class=\"ds-markdown-paragraph\"><strong>COFEPRIS sanitary notices<\/strong>\u00a0are not optional if your business involves food, health, or consumer products. Complying with regulations not only avoids penalties but also protects your customers and strengthens trust in your brand.<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>Remember:<\/strong><\/p>\n<ul>\n<li class=\"ds-markdown-paragraph\">Identify whether your business requires an operation notice or sanitary registration<\/li>\n<li class=\"ds-markdown-paragraph\">Designate a health responsible party if mandatory<\/li>\n<li class=\"ds-markdown-paragraph\">Keep your facilities and processes in order for inspections<\/li>\n<li class=\"ds-markdown-paragraph\">Complete the procedures before starting operations<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\">A regulated business is a reliable business.\u00a0<strong>Comply with COFEPRIS and operate with peace of mind.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If your business is related to food, beverages, supplements, cosmetics, health services, or medical products, you need to comply with\u00a0COFEPRIS&hellip;<\/p>\n","protected":false},"author":1,"featured_media":4553,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[50,36],"tags":[],"class_list":["post-4552","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-legal-en","category-planning"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>COFEPRIS Sanitary Notices: for Food and Health Businesses<\/title>\n<meta name=\"description\" content=\"Learn what COFEPRIS sanitary notices are, who needs them, types of procedures, and how to comply with health regulations in Mexico.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/victorvizcaino.com\/blog\/cofepris-sanitary-notices-mexico\/\" 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